Search on: BETA KARYOPHERINS 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   beta Karyopherins 
Descriptor Spanish:   beta Carioferinas 
Descriptor Portuguese:   beta Carioferinas 
Synonyms English:   Karyopherin-beta  
Tree Number:   D12.776.157.530.750.500.249
D12.776.543.585.750.500.249
D12.776.660.502.500
Definition English:   Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta. 
History Note English:   2002; use BETA KARYOPHERINS (NM) 1995-2001; for IMPORTIN-BETA use KARYOPHERINS (NM) 1995-2001 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   36193 
Unique Identifier:   D028961 

Occurrence in VHL: 		 

Similar:
  
DeCS SciELO LILACS LIS